Successful Treatment of Refractory Hailey-Hailey Disease with Dupilumab: A Case Report

Methotrexate for refractory Hailey-Hailey disease.

Editor We would like to report the use of methotrexate to treat a female patient with refractory, long standing Hailey–Hailey disease (HHD). To our knowledge, this is only the second case report of methotrexate being used to treat this disease. A 42-year-old woman presented to us with active skin lesions affecting both axillae, groins and lateral aspect of neck (Fig. 1) that had an ondulant cou...

Successful Treatment of Hailey-Hailey Disease with a Scanned Carbon Dioxide Laser

1. Wade TR, Ackerman AB. Cornoid lamellation. A histologic reaction pattern. Am J Dermatopathol 1980; 2: 5 ± 15. 2. Schamroth JM, Zlotogorski A, Gilead L. Porokeratosis of MibelliÐoverview and review of the literature. Acta Derm Venerol 1997; 77: 207 ± 213. 3. Fields LL, White CR Jr, Maziarz RT. Rapid development of disseminated super®cial porokeratosis after transplant induction therapy. Bone ...

A case of eczema herpeticum with hailey-hailey disease.

Eczema herpeticum is the dissemination of herpes simplex virus in the setting of a preexisting skin disease. Hailey-Hailey disease [familial benign chronic pemphigus] is a blistering dermatosis that is inherited as an autosomal dominant trait and it usually presents itself around the third or fourth decades. Coexistence of eczema herpeticum and Hailey-Hailey disease is an infrequent occurrence....

Refractory Hailey-Hailey Disease That Responded Well to Photodynamic Therapy.

of vascular origin. The most important differential diagnoses are angiosarcoma, which expresses endothelial markers such as CD31 and CD34, and chronic expansive hematoma, which presents as an encapsulated tumor filled with blood and neovasculature. What was interesting about this case, apart from the rarity of the condition, was the ease with which a giant vascular eccrine spiradenoma could be ...

Case Report A man with familial flexural rash: a case of Hailey-Hailey disease